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Research Highlight: Phosphorylation Networking

As seen on the cover of Cell (March 6th, 2009) Nevan Krogan, in collaboration with Kevan Shokat and colleagues, describes a comprehensive genetic analysis of the signaling machinery including all kinases and phosphatases using the E-Map approach. This work accurately recapitulated many well characterized signaling pathways and also identified unanticipated connections between different phosphorylation cascades. This approach lays the foundation for identifying combinations of genes, or genes operating at critical nodes at the intersection of signaling pathways, that can serve as appropriate therapeutic targets.

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News & Upcoming Events

QB3 Invitational Seminar
The Origin of Life in the Lab
Thursday, 2/11 from 12pm • Genentech Hall Auditorium

QB3 and iPQB welcome Gerald Joyce from the Scripps Institute. Hosted by the Chemistry and Chemical Biology Graduate Students, he will talk about "The Origin of Life in the Laboratory."

QB3 Invitational Seminar
Control by Phosphorylation
Wednesday, 2/24 from 2pm • Genentech Hall Auditorium

QB3 and iPQB welcome Louise Johnson from Oxford University who will present her research in "The structural basis for control by phosphorylation and protein kinase inhibitors." Hosted by the Stroud lab.

QB3 Invitational Seminar
Superresolution Imaging
Thursday, 2/25 from 12pm • Genentech Hall Auditorium

W.E. Moerner from Stanford University presents his research in "Superresolution Imaging and Trapping Single Biomolecules, In and Out of Cells." Sponsored by QB3 and iPQB, and hosted by the Matt Jacobson lab.

The Byers Bash
* save the date *
Friday, 3/12

The Byers Bash celebrates of the anniversary of the initial occupancy of Byers Hall in March of 2005. At the time, American Idol was becoming very popular and we chose to have our own version with a talent competition pitting floor against floor. Stay tuned for more updates!

QB3 Invitational Seminar
PKA Dynamics
Thursday, 3/18 from 12pm • Genentech Hall Auditorium

QB3 and iPQB welcome Susan Taylor from UC San Diego who will present on her research entitled:"PKA Dynamics: Liners, Loops and Tails." Joint hosted by the Jim Wells Lab and the Matt Jacobson Lab.


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Mini-Bio

Nevan Krogan

Nevan Krogan is an Assistant Professor in the Department of Cellular & Molecular Pharmacology with his lab in the 3rd floor-North neighborhood of Byers Hall. He originally came to qb3 in 2006 as a UCSF Fellow in the Systems Biology program after receiving his PhD at the University of Toronto. read more



coming soon...